Shadmand, Mehdi, Lucas, Tyler, Kelly, Madison, Hum, Julia, and Sharma, Curren Robling, Alexander

Context: In states of health, bone mass is sustained in a coordinated effort by osteoblasts, osteoclasts, and osteocytes. WNT signaling through low-density lipoprotein receptor related protein 5/6 (LRP5/LRP6) is one of the...

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Farach-Carson Mary, Sharma, Karan, Kelly, Madison, Hum, Julia, Noonan, Megan, Yi, Xin, and Robling, Alexander

Mechanical loading is critical for bone remodeling. Voltage sensitive calcium channels (VSCCs) influence bone development and responses to loading. The α₂δ₁ VSCC subunit regulates osteocyte...

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Thompson, William R., Kelly, Madison, Bender, Cecelia, Hum, Julia, Oberhelman, Forrest, and Young, Collin

Voltage sensitive calcium channels (VSCCs) are key components in coordinating extracellular signaling that influence calcium (Ca2+) influx and subsequent downstream signaling in a variety of tissues including bone. Previous...

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