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3-2-2018

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Friedreich ataxia

Identification of p38 MAPK as a novel therapeutic target for Friedreich's ataxia.

Correspondências de palavras-chave:

O Criador:

to be added

Descrição:

Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...

Tipo:

Article
Identification of p38 MAPK as a Novel Therapeutic Target for Friedreich’s Ataxia

Correspondências de palavras-chave:

... shRNA in cells, (2) we used cells into which an empty vector was introduced as a control and, (3) we ...

... | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 3 www.nature.com/scientificreports/ Figure 3 ...

... www.nature.com/scientificreports OPEN Received: 27 July 2017 Accepted: 7 March 2018 Published: xx ...

... include those by Koeppen and Mazurkiewicz1, Collins2, and Gomes and Santos)3. In the majority of cases ...

... @mail.med.upenn.edu) SCIENTIFIC Reports | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 1 www.nature.com ...

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O Criador:

Lin, Daniel, Tobias, John W., Cotticelli, M. Gracia, Ruff, Eric, Wang, Yongping, Xia, Shujuan, Wilson, Robert B., and Kaur, Avinash

Descrição:

Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...

Tipo:

Article