Pathogenic variant
A founder CHEK2 pathogenic variant in association with kidney cancer
Holman, M, Steding, Catherine, Tucker, M, and Brooks, K
The gene CHEK2 is located at 22q12.1 and codes for the protein checkpoint kinase 2, a protein that functions in cell cycle regulation and is a known tumor suppressor. CHEK2 is activated due to DNA damage generating a cascade of...
Article
Work1
Article1
Brooks, K1
Holman, M1
Steding, Catherine1
Tucker, M1
CHEK21
Clear Cell renal carcinoma1
Genetic Counseling1
Genetic Testing1
Kidney Cancer1
English1
Published by Elsevier Inc.1
20211
Faculty Publications and Research - MUCOM1
Marian University1