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Doi: 10.18632/aging.204515

Keyword

sphingolipid metabolism

The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

Keyword matches:

... www.aging-us.com AGING 2023, Vol. 15, No. 3 Research Paper The lipidomes of C. elegans with ...

... aging Trisha A. Staab1, Grace McIntyre1, Lu Wang2, Joycelyn Radeny4, Lisa Bettcher3, Melissa Guillen1 ...

... -0001-8123-536X Keywords: lipidomics, aging, sphingolipid metabolism, C. elegans, fatty acid metabolism ...

... characterize metabolic changes during aging in C. elegans. fatty acids (FA), triacylglycerols (TAG ...

... ), sphingolipids (SL), and phospholipids (PL) have been identified as targets in lipid signatures related to aging ...

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Creator:

Staab, Trisha, McIntyre, Grace, Bromley, S., Raftery, D., Chan, Jason, Wang, L., Radeny, J., Bettcher, L., Guillen, Melissa, Peck, M. , and Kalil, A.

Description:

Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age...

Type:

Research Paper