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4/5/1952

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Faculty Publications and Research - MUCOM

Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

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... for 4 hours, as indicated. A, Western blot for phospho-Smad1/5/8 and Id1 shows 4-PBA restores ...

... treated with 4-PBA (Figure 6A). 4-PBA restored BMP2 induced Smad1/5/8 phosphorylation (Figure 6B) and BMP ...

... Center, Nashville, Tennessee, United States of America, 4 Department of Pediatrics, Division of Pediatric ...

... Pulmonary Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, 5 ...

... 4-PBA and TUDCA partially restore cell surface expression of Bmpr2Ex2 in PECs, suggesting that the ...

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Creator:

Frump, A.L., Hamid, R., de Caestecker, M., Austin, E.D., and Lowery, Jonathan W.

Description:

More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...

Type:

Article
Soft Tissue Manipulation Alters RANTES/CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain

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... . Lowery 1,2,3,5,8,9, * 1 2 3 4 5 6 7 8 9 * Citation: Marciano, C.L.; Hiland, T.A.; Jackson, K.L.; Street ...

... ) ligand 5 (CCL5) and increased soft tissue levels of Interleukin (IL)-4, which are pro-inflammatory and ...

... detected on the membrane including IL-4, Granulo10/CXCL-10, CXCL-5/Lipopolysaccharide-Induced CXCarray ...

... . 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. Lucas, J.W.; Connor, E.M.; Bose, J. Back, Lower Limb ...

... /CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain Carmela L. Marciano 1,2, , Taylor ...

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Creator:

Marciano, Carmela L., Hiland, Taylor A., Chu, TM, Kang, Kyung S., Lowery, Jonathan W., Jackson, Krista L., Street, Sierra, Maris, Carson, Ehrsam, Andrew, Hum, Julia M. , and Loghmani, M

Description:

Low back pain (LBP) is a common musculoskeletal complaint that can impede physical function and mobility. Current management often involves pain medication, but there is a need for non-pharmacological and non-invasive...

Type:

Article

Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

Soft Tissue Manipulation Alters RANTES/CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain

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