... does not impact SMAD 2/3 phosphorylation. Such also supports the signaling competency of W-20-17 cells ...
... negatively influences bone mass through action of the effectors SMAD2/3. Recent studies from our lab suggest ...
... osteogenic cell line W-20-17. We first confirmed that W-20-17 cells respond to exogenous stimulation by BMP2 ...
... mechanism allowing for this relationship, we treated W-20-17 cells with SB431542, which is an intracellular ...
... ligand-dependent but occurs upstream of SMAD2/3 activation. Noggin is a BMP-specific antagonist protein ...