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ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

Correspondências de palavras-chave:: ... Research ABT-510 Is an Effective Chemopreventive Agent in the Mouse 4-Nitroquinoline 1-Oxide Model of Oral ...

... Carcinogenesis Rifat Hasina,1 Leslie E. Martin,1 Kristen Kasza,2 Colleen L. Jones,1 Asif Jalil1 and Mark W ...

... with preventive strategies. Using the 4-nitroquinoline 1-oxide (4-NQO) mouse model, we sought to define ...

... angiogenesis can slow/delay the development of HNSCC. We determined that 8 weeks of 100 g/mL 4-NQO in the ...

... year (1). Despite numerous advances in therapy, the long-term survival for these patients has remained ...

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O Criador:: Martin, Leslie E., Jones, Colleen L., Hasina, Rifat, Jalil, Asif, Lingen, Mark W., and Kasza, Kristen
Descrição:: Despite numerous advances, the 5-year survival rate for head and neck squamous cell cancer (HNSCC) has remained largely unchanged. This poor outcome is due to several variables, including the development of multiple primary...
Tipo:: Article

BMP Signaling in Vascular Development and Disease.

Correspondências de palavras-chave:
O Criador:: Lowery, Jonathan W. and de Caestecker, M.
Descrição:: Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis...
Tipo:: Article

Christian Discipleship: The Primordial Model for Comprehensive Catholic Youth Ministry

Correspondências de palavras-chave:: ... 1 ...

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O Criador:: Canales, Art
Descrição:: This article addresses Christian discipleship: (1) as a primordial model for comprehensive Catholic youth ministry and (2) as a developmental theology for contemporary youth ministry. Moreover, it situates Christian...
Tipo:: Article

Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis.

Correspondências de palavras-chave:: ... , comprehensive treatment plans must include improved chemopreventive strategies. Using the 4-nitroquinoline 1 ...

... chemopreventive agent. CBA mice were fed 4-NQO (100 g/mL) in their drinking water for 8 weeks and then randomized ...

... the sixth most common malignancy in the world today (1). There will be over 35,000 new cases in the ...

... . First, OSCC is often diagnosed at an advanced stage. The 5-year Authors' Affiliations: Departments of 1 ...

... -0135 Zhou et al. wound healing, reproduction, arthritis, and tumor formation (8). Because of its ...

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O Criador:: Mankame, Tanmayi P., Zhou, Guolin, Wroblewski, Kristen, Lingen, Mark W., Doci, Colleen L., and Hasina, Rifat
Descrição:: Despite recent therapeutic advances, several factors, including field cancerization, have limited improvements in long-term survival for oral squamous cell carcinoma (OSCC). Therefore, comprehensive treatment plans must include...
Tipo:: Article

A method to switch from oral dopamine agonists to rotigotine in patients with restless legs syndrome and mild augmentation.

Correspondências de palavras-chave:
O Criador:: Winkelman, John W., Schoerning, Laura, Platt, Samuel, Mei, Leslie A, and Mackie, Susan E
Descrição:: BACKGROUND: We examined the short- and long-term efficacy and tolerability of a cross-titration algorithm from oral dopamine agonists to the rotigotine transdermal patch in patients dissatisfied with their restless legs...
Tipo:: Article

N-linked Glycosylation of the Bone Morphogenetic Protein Receptor Type 2 (BMPR2) Enhances Ligand Binding

Correspondências de palavras-chave:: ... ; 71(16): 31653172. doi:10.1007/s00018-013-1541-8. N-linked glycosylation of the Bone Morphogenetic ...

... complex of type 1 and type 2 receptors to activate downstream transcription factors. It is well ...

... interacting with a hetero-oligomeric complex of type 1 and type 2 receptors to activate downstream ...

... across all animals [1], gene duplication events are * To whom correspondence should be addressed: Vicki ...

... example, the mammalian genome contains approximately twenty BMP ligands, seven type 1 receptors (ALK1/2/3 ...

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O Criador:: Amich, J.M., Andonian, A., Rosen, V., and Lowery, Jonathan W.
Descrição:: The bone morphogenetic protein (BMP) signaling pathway is essential for normal development and tissue homeostasis. BMP signal transduction occurs when ligands interact with a complex of type 1 and type 2 receptors to activate...
Tipo:: Article

Navigating the Third Frontier of Antimicrobial Therapy to Support Women’s Health

Correspondências de palavras-chave:: ... Obstetrics and Gynecology, 10, 1011-1035. https://doi.org/10.4236/ojog.2020.1080096 Received: July 1, 2020 ...

... Infection, Antibiotic Therapy, Antimicrobial Resistance, Quiescent Microorganisms, Mechanisms 1 ...

... babies infected [1]. This occurs in the face of effective methods for screening, even in a high-resource ...

... resistance to pyrimethamine and sulfadiazine and clinical consequences remain under scrutiny [8]. Another ...

... complex 1 (TORC1) pathway alters cell growth by various mechanisms: cell cycle initiation and translation ...

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O Criador:: Larsen, Bryan, Yar, Neela, and Whitman, Emma OMS-2
Descrição:: This paper explores one of the underappreciated reasons for lack of efficacy in certain cases of antimicrobial therapy, namely the occurrence of a non-genetic resistance to antimicrobial drugs due to a metabolic quiescence of...
Tipo:: Article

Soft Tissue Manipulation Alters RANTES/CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain

Correspondências de palavras-chave:: ... . Lowery 1,2,3,5,8,9, * 1 2 3 4 5 6 7 8 9 * Citation: Marciano, C.L.; Hiland, T.A.; Jackson, K.L.; Street ...

... breaking down the extracellular matrix [8]. TIMP-1 also has cytokine-line functions, such as binding to ...

... types of LBP, including CXCL5/LIX (the murine homolog of IL-8), GM-CSF, ICAM-1, IL1-ra, IL-6, IP-10 ...

... Correspondence: jlowery@marian.edu; Tel./Fax: +1-317-955-6621 These authors contributed equally to this work ...

... (LIX) which is the murine homologue of IL-8, CXCL-7, Granulocyte-Macrophage-Colony Simulating Factor ...

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O Criador:: Marciano, Carmela L., Hiland, Taylor A., Chu, TM, Kang, Kyung S., Lowery, Jonathan W., Jackson, Krista L., Street, Sierra, Maris, Carson, Ehrsam, Andrew, Hum, Julia M. , and Loghmani, M
Descrição:: Low back pain (LBP) is a common musculoskeletal complaint that can impede physical function and mobility. Current management often involves pain medication, but there is a need for non-pharmacological and non-invasive...
Tipo:: Article

World Neurosurgery: Case Reports Surgical Management of Trigeminal Neuralgia in Children

Correspondências de palavras-chave:
O Criador:: Chicoine, Nicole H. OMS-3, Yaacoubm A.P., Raskin, J. S., and Jea, A.
Descrição:: BACKGROUND: Trigeminal Neuralgia (TN) is a well-recognized facial pain syndrome. Discrete forms with disparate pain symptoms include TN1 and TN2, however, atypical facial pain includes neuralgiform pain along a spectrum. The...
Tipo:: Article

ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

BMP Signaling in Vascular Development and Disease.

Christian Discipleship: The Primordial Model for Comprehensive Catholic Youth Ministry

Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis.

A method to switch from oral dopamine agonists to rotigotine in patients with restless legs syndrome and mild augmentation.

N-linked Glycosylation of the Bone Morphogenetic Protein Receptor Type 2 (BMPR2) Enhances Ligand Binding

Navigating the Third Frontier of Antimicrobial Therapy to Support Women’s Health

Soft Tissue Manipulation Alters RANTES/CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain

World Neurosurgery: Case Reports Surgical Management of Trigeminal Neuralgia in Children

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