Inadequate pain management during a laparoscopic cholecystectomy can affect postoperative hemodynamics, impair recovery, and extend hospital stay. The use of opioid medications during and after surgeries can reduce postoperative pain, however, the complications of opioid use such as nausea, vomiting, respiratory depression with the associated cardiovascular implications, and pneumonia can also impair recovery from surgery, cause postoperative discomfort, prolong hospital stay and could potentially cause opioid abuse in some patient population with surgical exposure. Numerous studies have reported the crucial role of administering preoperative or intraoperative non-opioid medications to mitigate postoperative pain. The purpose of this project is to utilize preoperative non-opioid multimodal analgesics to manage postoperative pain and reduce intraoperative and postoperative opioid use. Eight patients were studied in this project to determine the efficacy of preoperative acetaminophen, in combination with gabapentin and ibuprofen to reduce post-operative pain perception and post-operative rescue opioid administration. The study determined that preoperative pain medications, intraoperative pain medications, duration of surgery, gender and age can all influence postoperative pain. Also, among the participants who perceived pain after surgery despite receiving preoperative treatment, pain was more significant among females compared to males, and pain rating was highest within the first 15 minutes and reduced as time progressed. Further studies need to include more variables such as comorbidities, and ethnic differences in how they affect postoperative pain. Also, more studies are needed to ascertain the best combination of preoperative non-opioid treatment regimen that can maximally reduce intraoperative and postoperative pain and opioid use.

Creator

• Nnoruo, Valine C.

• Enoweyere, Bessem

Language

• English

Keyword

• laparoscopic cholecystectomy

• pain management

• postoperative hemodynamics

• opioid medications

• postoperative discomfort

• prolonged hospital stay

• intraoperative non-opioid medications

Date created

• 2023

Resource type

• Research Paper

Rights statement

• http://rightsstatements.org/vocab/InC/1.0/